1-NM-PP1
Product Sizes
50 mg
£ POA
HY-13942-50MG
5 mg
£ POA
HY-13942-5MG
10 mg
£ POA
HY-13942-10MG
100 mg
£ POA
HY-13942-100MG
10mM/1mL
£ POA
HY-13942-10MM
25 mg
£ POA
HY-13942-25MG
About this Product
- SKU:
- HY-13942
- Additional Names:
- PP1 Analog II
- CAS Number:
- 221244-14-0
- Extra Details:
- 1-NM-PP1; a cell-permeable PP1 analog; is a potent Src family kinases inhibitor with IC50s of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1; respectively[1][2].
- Molecular Weight:
- 331.41
- Purity:
- 99.17
- References:
- [1]Bishop A C, et al. Generation of Monospecific Nanomolar Tyrosine Kinase Inhibitors via a Chemical Genetic Approach. Journal of the American Chemical Society, 1999, 121(4):627-631.|[2]Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401.|[3]Larochelle S, et al. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol Cell. 2007 Mar 23;25(6):839-50.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Protein Tyrosine Kinase/RTK
