1-Naphthyl PP1
Product Sizes
5 mg
£ POA
HY-13941-5MG
100 mg
£ POA
HY-13941-100MG
50 mg
£ POA
HY-13941-50MG
25 mg
£ POA
HY-13941-25MG
10 mg
£ POA
HY-13941-10MG
10mM/1mL
£ POA
HY-13941-10MM
About this Product
- SKU:
- HY-13941
- Additional Names:
- 1-NA-PP 1
- CAS Number:
- 221243-82-9
- Extra Details:
- 1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn; c-Abl; CDK2 and CAMK II with IC50s of 1.0; 0.6; 0.6; 18 and 22 μM; respectively[1][2][3].
- Molecular Weight:
- 317.39
- Purity:
- 99.36
- References:
- [1]Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401.|[2]Tandon M, et al. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One. 2013 Sep 23;8(9):e75601.|[3]Maiya R, et al. Selective chemical genetic inhibition of protein kinase C epsilon reduces ethanol consumption in mice. Neuropharmacology. 2016 Aug;107:40-48.
- Research Area:
- Cancer;Inflammation/Immunology;Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Protein Tyrosine Kinase/RTK
