TJ-M2010-5
Product Sizes
50 mg
£ POA
HY-139397-50MG
10 mg
£ POA
HY-139397-10MG
5 mg
£ POA
HY-139397-5MG
100 mg
£ POA
HY-139397-100MG
25 mg
£ POA
HY-139397-25MG
10mM/1mL
£ POA
HY-139397-10MM
About this Product
- SKU:
- HY-139397
- CAS Number:
- 1357471-57-8
- Extra Details:
- TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization; and the TLR/MyD88 signal pathway[1][2]. TJ-M2010-5 can be used for the research of myocardial ischemia/reperfusion injury (MIRI)[2].
- Molecular Weight:
- 406.54
- Purity:
- 99.85
- References:
- [1]Lin Xie, et al. Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. J Natl Cancer Inst. 2015 Dec 28;108(4):djv364.|[2]Yan Miao,et al. Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury.Am J Transl Res. 2020 Sep 15;12(9):5151-5169.
- Research Area:
- Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
