SK-575
Product Sizes
5 mg
£ POA
HY-139156-5MG
100 mg
£ POA
HY-139156-100MG
10 mg
£ POA
HY-139156-10MG
25 mg
£ POA
HY-139156-25MG
50 mg
£ POA
HY-139156-50MG
10mM/1mL
£ POA
HY-139156-10MM
About this Product
- SKU:
- HY-139156
- Application:
- Antibody Microarray
- CAS Number:
- 2523016-96-6
- Extra Details:
- SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1; with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations[1].
- Molecular Weight:
- 876.97
- Purity:
- 99.93
- References:
- [1]Cao C, et al. Discovery of SK-575 as a Highly Potent and Efficacious Proteolysis-Targeting Chimera Degrader of PARP1 for Treating Cancers. J Med Chem. 2020 Oct 8;63(19):11012-11033.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Epigenetics;PROTAC
