Hydroxyfasudil (hydrochloride)
Product Sizes
5 mg
£ POA
HY-13911A-5MG
50 mg
£ POA
HY-13911A-50MG
10 mg
£ POA
HY-13911A-10MG
100 mg
£ POA
HY-13911A-100MG
25 mg
£ POA
HY-13911A-25MG
10mM/1mL
£ POA
HY-13911A-10MM
About this Product
- SKU:
- HY-13911A
- Additional Names:
- HA-1100 hydrochloride; HA 1100 hydrochloride; HA1100 hydrochloride
- CAS Number:
- 155558-32-0
- Extra Details:
- Hydroxyfasudil hydrochloride is a ROCK inhibitor; with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2; respectively.
- Molecular Weight:
- 343.83
- Purity:
- 98.99
- References:
- [1]Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1.|[2]Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16(10):842-7.|[3]Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66(4):325-31.
- Research Area:
- Inflammation/Immunology; Cardiovascular Disease; Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
