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Proteins and Peptides

Hydroxyfasudil

Product Sizes
5 mg
£ POA
HY-13911-5MG
10 mg
£ POA
HY-13911-10MG
50 mg
£ POA
HY-13911-50MG
25 mg
£ POA
HY-13911-25MG
100 mg
£ POA
HY-13911-100MG
10mM/1mL
£ POA
HY-13911-10MM
About this Product
SKU:
HY-13911
Additional Names:
HA-1100
CAS Number:
105628-72-6
Extra Details:
Hydroxyfasudil is a ROCK inhibitor; with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2; respectively.
Molecular Weight:
307.38
Purity:
98.78
References:
[1]Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1.|[2]Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16(10):842-7.|[3]Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66(4):325-31.
Research Area:
Cancer; Inflammation/Immunology; Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
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