Clevudine
Product Sizes
100 mg
£ POA
HY-13859-100MG
50 mg
£ POA
HY-13859-50MG
About this Product
- SKU:
- HY-13859
- Additional Names:
- L-FMAU
- CAS Number:
- 163252-36-6
- Extra Details:
- Clevudine (L-FMAU); a nucleoside analog of the unnatural L-configuration; has potent anti-HBV activity with long half-life; low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice[1][2][3].
- Molecular Weight:
- 260.22
- Purity:
- 99.84
- References:
- [1]Asselah T, et al. Clevudine: a promising therapy for the treatment of chronic hepatitis B. Expert Opin Investig Drugs. 2008;17(12):1963-1974.|[2]Yoo BC, et al. Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression. Hepatology. 2007;46(4):1041-1048.|[3]Smee DF, et, al. Progress in the discovery of compounds inhibiting orthopoxviruses in animal models. Antivir Chem Chemother. 2008;19(3):115-24.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Anti-infection;Cell Cycle/DNA Damage
