ALC-0315
Product Sizes
50 mg
£ POA
HY-138170-50MG
1 g
£ POA
HY-138170-1G
500 mg
£ POA
HY-138170-500MG
25 mg
£ POA
HY-138170-25MG
100 mg
£ POA
HY-138170-100MG
10 mg
£ POA
HY-138170-10MG
10mM/1mL
£ POA
HY-138170-10MM
About this Product
- SKU:
- HY-138170
- CAS Number:
- 2036272-55-4
- Extra Details:
- ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine[1].
- Molecular Weight:
- 766.27
- Purity:
- 99.72
- References:
- [1]Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898-900.|[2]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19(7):2175-2182.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Anti-infection;Metabolic Enzyme/Protease
