Tenofovir amibufenamide
Product Sizes
100 mg
£ POA
HY-137453-100MG
50 mg
£ POA
HY-137453-50MG
25 mg
£ POA
HY-137453-25MG
1 mg
£ POA
HY-137453-1MG
10 mg
£ POA
HY-137453-10MG
5 mg
£ POA
HY-137453-5MG
10mM/1mL
£ POA
HY-137453-10MM
About this Product
- SKU:
- HY-137453
- Additional Names:
- HS-10234
- CAS Number:
- 1571076-26-0
- Extra Details:
- Tenofovir amibufenamide (HS-10234); a Tenofovir prodrug; is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV; and can be used for chronic hepatitis B (CHB) study[1][2].
- Molecular Weight:
- 490.49
- Purity:
- 99.67
- References:
- [1]Zhihong Liu, et al. Randomised clinical trial: 48 weeks of treatment with tenofovir amibufenamide versus tenofovir disoproxil fumarate for patients with chronic hepatitis B. Aliment Pharmacol Ther. 2021 Nov;54(9):1134-1149.|[2]Hong Zhang, et al. Randomised clinical trial: safety, efficacy and pharmacokinetics of HS-10234 versus tenofovir for the treatment of chronic hepatitis B infection. Aliment Pharmacol Ther. 2021 Jan;53(2):243-252.|[3]Hong X, et al., Improved pharmacokinetics of tenofovir ester prodrugs strengthened the inhibition of HBV replication and the rebalance of hepatocellular metabolism in preclinical models. Front Pharmacol. 2022 Aug 29;13:932934.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection
