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Proteins and Peptides

(+)-ITD-1

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HY-137063-1EACH
About this Product
SKU:
HY-137063
CAS Number:
1409968-46-2
Extra Details:
(+)-ITD-1 is an inhibitor for TGF-β; that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte; and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs)[1].
Molecular Weight:
415.52
References:
[1]Willems E, et al., Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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