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Azide-PEG4-VC-PAB-Doxorubicin

Product Sizes
50 mg
£ POA
HY-136288-50MG
10 mg
£ POA
HY-136288-10MG
1 mg
£ POA
HY-136288-1MG
100 mg
£ POA
HY-136288-100MG
25 mg
£ POA
HY-136288-25MG
5 mg
£ POA
HY-136288-5MG
About this Product
SKU:
HY-136288
Application:
Antibody Microarray
Extra Details:
Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC)[1]. Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
1222.25
Purity:
99.62
References:
[1]Hayward R, et al. Doxorubicin cardiotoxicity in the rat: an in vivo characterization. J Am Assoc Lab Anim Sci. 2007 Jul;46(4):20-32.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related
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