BSJ-04-132
Product Sizes
50 mg
£ POA
HY-136252-50MG
100 mg
£ POA
HY-136252-100MG
10 mg
£ POA
HY-136252-10MG
25 mg
£ POA
HY-136252-25MG
5 mg
£ POA
HY-136252-5MG
10mM/1mL
£ POA
HY-136252-10MM
About this Product
- SKU:
- HY-136252
- CAS Number:
- 2349356-39-2
- Extra Details:
- BSJ-04-132 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC); with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1; respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity[1].
- Molecular Weight:
- 819.91
- Purity:
- 99.07
- References:
- [1]Baishan Jiang, et al. Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PROTAC
