BSJ-03-204 (triTFA)
Product Sizes
50 mg
£ POA
HY-136250A-50MG
25 mg
£ POA
HY-136250A-25MG
10 mg
£ POA
HY-136250A-10MG
5 mg
£ POA
HY-136250A-5MG
100 mg
£ POA
HY-136250A-100MG
10mM/1mL
£ POA
HY-136250A-10MM
About this Product
- SKU:
- HY-136250A
- Extra Details:
- BSJ-03-204 triTFA is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 triTFA is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC); with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1; respectively. BSJ-03-204 triTFA does not induce IKZF1/3 degradation and has anti-cancer activity[1].
- Molecular Weight:
- 1174.97
- Purity:
- 99.87
- References:
- [1]Baishan Jiang, et al. Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PROTAC
