BSJ-03-204
Product Sizes
10 mg
£ POA
HY-136250-10MG
5 mg
£ POA
HY-136250-5MG
100 mg
£ POA
HY-136250-100MG
50 mg
£ POA
HY-136250-50MG
1 mg
£ POA
HY-136250-1MG
25 mg
£ POA
HY-136250-25MG
10mM/1mL
£ POA
HY-136250-10MM
About this Product
- SKU:
- HY-136250
- CAS Number:
- 2349356-09-6
- Extra Details:
- BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC); with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1; respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity[1].
- Molecular Weight:
- 832.90
- Purity:
- 99.76
- References:
- [1]Baishan Jiang, et al. Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PROTAC
