HS-243
Product Sizes
10 mg
£ POA
HY-134911-10MG
100 mg
£ POA
HY-134911-100MG
5 mg
£ POA
HY-134911-5MG
50 mg
£ POA
HY-134911-50MG
25 mg
£ POA
HY-134911-25MG
10mM/1mL
£ POA
HY-134911-10MM
About this Product
- SKU:
- HY-134911
- CAS Number:
- 848249-10-5
- Extra Details:
- HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor; with IC50 values of 20 and 24 nM. HS-243 shows minimal TAK1 (transforming growth factor β-activated kinase 1) inhibition activity; with a IC50 of 0.5 μM. HS-243 shows anti-inflammatory and anticancer activity[1].
- Molecular Weight:
- 324.33
- Purity:
- 99.95
- References:
- [1]Scarneo SA, et al. A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase. J Biol Chem. 2020 Feb 7;295(6):1565-1574.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Immunology/Inflammation
