(1S;2S)-ML-SI3
Product Sizes
100 mg
£ POA
HY-134819-100MG
25 mg
£ POA
HY-134819-25MG
5 mg
£ POA
HY-134819-5MG
10 mg
£ POA
HY-134819-10MG
50 mg
£ POA
HY-134819-50MG
10mM/1mL
£ POA
HY-134819-10MM
About this Product
- SKU:
- HY-134819
- Additional Names:
- (+)-trans-ML-SI3
- Application:
- Antibody Microarray
- CAS Number:
- 2563870-87-9
- Extra Details:
- (1S;2S)-ML-SI3 is a trans-isomer of ML-SI3 that targets all three isoforms of TRPML. (1S;2S)-ML-SI3 is an activator of TRPML2 and TRPML3 (EC50=2.7 μM/10.8 μM) and a potent inhibitor of TRPML1 (IC50=5.9 μM)[1].
- Molecular Weight:
- 429.58
- Purity:
- 99.96
- References:
- [1]Leser C, et al. Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3. Eur J Med Chem. 2021 Jan 15;210:112966.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel;Neuronal Signaling
