SM-102
Product Sizes
50 mg
£ POA
HY-134541-50MG
10 mg
£ POA
HY-134541-10MG
25 mg
£ POA
HY-134541-25MG
100 mg
£ POA
HY-134541-100MG
10mM/1mL
£ POA
HY-134541-10MM
1 g
£ POA
HY-134541-1G
5 mg
£ POA
HY-134541-5MG
About this Product
- SKU:
- HY-134541
- CAS Number:
- 2089251-47-6
- Extra Details:
- SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines[1][2].
- Molecular Weight:
- 710.17
- Purity:
- 99.97
- References:
- [1]Staci Sabnis, et al. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates. Mol Ther. 2018 Jun 6;26(6):1509-1519.|[2]Escalona-Rayo O, et al. In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy. Biomed Pharmacother. 2023 Sep;165:115065.|[3]Cho HY, et al. Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6(undecyloxy)hexyl]amino]-octanoate (SM-102), a Cationic Lipid. Biomedicines. 2021 Oct 1;9(10):1367.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Metabolic Enzyme/Protease
