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Proteins and Peptides

(Rac)-Indoximod

Product Sizes
50 mg
HY-133897-50MG
100 mg
HY-133897-100MG
About this Product
SKU:
HY-133897
Additional Names:
1-Methyl-DL-tryptophan; (Rac)-NLG-8189
CAS Number:
26988-72-7
Extra Details:
(Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine 2;3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1; Fas; and FasL genes[1].
Molecular Weight:
218.26
Purity:
99.60
References:
[1]Jun-Won Lee,et al. Co-treatment with interferon-γ and 1-methyl tryptophan ameliorates cardiac fibrosis through cardiac myofibroblasts apoptosis. Mol Cell Biochem. 2019 Aug;458(1-2):197-205.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Metabolic Enzyme/Protease
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