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Proteins and Peptides

(S)-Sunvozertinib

Product Sizes
10 mg
£ POA
HY-132842A-10MG
100 mg
£ POA
HY-132842A-100MG
25 mg
£ POA
HY-132842A-25MG
50 mg
£ POA
HY-132842A-50MG
5 mg
£ POA
HY-132842A-5MG
250 mg
£ POA
HY-132842A-250MG
500 mg
£ POA
HY-132842A-500MG
10mM/1mL
£ POA
HY-132842A-10MM
About this Product
SKU:
HY-132842A
Additional Names:
(S)-DZD9008
CAS Number:
2370013-49-1
Extra Details:
(S)-Sunvozertinib ((S)-DZD9008); the S-enantiomer of Sunvozertinib; shows inhibitory activity against EGFR exon 20 NPH and ASV insertions; EGFR L858R/T790M mutation and Her2 exon20 YVMA insertion (IC50=51.2 nM; 51.9 nM; 1 nM; and 21.2 nM; respectively). (S)-Sunvozertinib also inhibits BTK[1].
Molecular Weight:
584.08
Purity:
99.05
References:
[1]Zhengtao LI, et al. Erbb/btk inhibitors. WO2019149164A1.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
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