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Proteins and Peptides

(R)-(-)-Felodipine-d5

Product Sizes
1 mg
HY-132670S-1MG
About this Product
SKU:
HY-132670S
CAS Number:
1217744-87-0
Extra Details:
(R)-(-)-Felodipine-d5 is the deuterium labeled (R)-(-)-Felodipine. (R)-(-)-Felodipine is the S enantiomer of Felodipine. Felodipine; a dihydropyridine; is a potent; vasoselective calcium channel antagonist. Felodipine lowers blood pressure (BP) by selective action on vascular smooth muscle; especially in the resistance vessels. Felodipine; an anti-hypertensive agent; induces autophagy. Felodipine can cross the blood-brain barrier[1][2][3].
Molecular Weight:
389.28
References:
[1]Johnson JD, et al. Calcium and calmodulin antagonists binding to calmodulin and relaxation of coronary segments. J Pharmacol Exp Ther. 1983;226(2):330-334.;Siddiqi FH, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to r|[2]Siddiqi FH, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nat Commun. 2019 Apr 18;10(1):1817.|[3]Siddiqi FH, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nat Commun. 2019 Apr 18;10(1):1817.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules