Droxinostat
Product Sizes
5 mg
£ POA
HY-13267-5MG
50 mg
£ POA
HY-13267-50MG
10 mg
£ POA
HY-13267-10MG
25 mg
£ POA
HY-13267-25MG
100 mg
£ POA
HY-13267-100MG
10mM/1mL
£ POA
HY-13267-10MM
About this Product
- SKU:
- HY-13267
- Additional Names:
- NS 41080
- Application:
- Antibody Microarray
- CAS Number:
- 99873-43-5
- Extra Details:
- Droxinostat (NS 41080) is a histone deacetylase (HDAC) inhibitor. Droxinostat selectively inhibits HDAC3; HDAC6; and HDAC8 with IC50 values of 16.9 μM; 2.47 μM; and 1.46 μM; respectively. Droxinostat can be used for the research of hepatocellular carcinoma (HCC)[1][2].
- Molecular Weight:
- 243.69
- Purity:
- 99.08
- References:
- [1]Liu J, et al. Droxinostat, a Histone Deacetylase Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cell Lines via Activation of the Mitochondrial Pathway and Downregulation of FLIP. Transl Oncol. 2016 Feb;9(1):70-8.|[2]Wood TE et al. Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands. Mol Cancer Ther. 2010 Jan;9(1):246-56.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Cell Cycle/DNA Damage;Epigenetics
