Fitusiran
Product Sizes
5 mg
£ POA
HY-132587-5MG
1 mg
£ POA
HY-132587-1MG
10 mg
£ POA
HY-132587-10MG
About this Product
- SKU:
- HY-132587
- Additional Names:
- ALN-AT3SC; SAR439774
- Application:
- Electron Microscopy
- CAS Number:
- 1499251-18-1
- Extra Details:
- Fitusiran (ALN-AT3SC) is a siRNA strategy. Fitusiran delivers siRNA targeting the SERPINC1 gene in hepatocytes to inhibit antithrombin synthesis. Fitusiran enhances thrombin activity and increases Thrombin generation; thereby restoring hemostatic function. Fitusiran can be used in hemophilia-related research[1][2][3].
- Molecular Weight:
- 16248.2 (AS: 7675 + SS: 8573.2)
- Purity:
- 94.74
- References:
- [1]Pasi KJ, et al. Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort. J Thromb Haemost. 2021;19(6):1436-1446.
- Research Area:
- Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Epigenetics;Metabolic Enzyme/Protease
