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Proteins and Peptides

(Rac)-PF-4136309

Product Sizes
50 mg
£ POA
HY-13245B-50MG
10 mg
£ POA
HY-13245B-10MG
100 mg
£ POA
HY-13245B-100MG
25 mg
£ POA
HY-13245B-25MG
1 mg
£ POA
HY-13245B-1MG
5 mg
£ POA
HY-13245B-5MG
About this Product
SKU:
HY-13245B
Additional Names:
(Rac)-INCB8761
CAS Number:
857679-55-1
Extra Details:
(Rac)-PF-4136309 is an isoform of PF-4136309 (HY-13245); which is a potent; selective; and orally bioavailable CCR2 antagonist; with IC50s of 5.2 nM; 17 nM and 13 nM for human; mouse and rat CCR2.
Molecular Weight:
568.59
Purity:
98.0
References:
[1]Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Immunology/Inflammation
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