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Proteins and Peptides

(s)-PF-4136309

Product Sizes
5 mg
£ POA
HY-13245A-5MG
10 mg
£ POA
HY-13245A-10MG
100 mg
£ POA
HY-13245A-100MG
50 mg
£ POA
HY-13245A-50MG
10mM/1mL
£ POA
HY-13245A-10MM
25 mg
£ POA
HY-13245A-25MG
About this Product
SKU:
HY-13245A
Additional Names:
(s)-INCB8761
Application:
Electron Microscopy
CAS Number:
1372407-07-2
Extra Details:
(s)-PF-4136309 is the isomer of PF-4136309 (HY-13245); and can be used as an experimental control. PF-4136309 is a potent; selective; and orally bioavailable CCR2 antagonist; with IC50s of 5.2 nM; 17 nM and 13 nM for human; mouse and rat CCR2.
Molecular Weight:
568.59
Purity:
98.93
References:
[1]Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918.
Research Area:
Endocrinology; Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Immunology/Inflammation;Others
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