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Proteins and Peptides

CBP/p300-IN-12

Product Sizes
5 mg
£ POA
HY-132197-5MG
100 mg
£ POA
HY-132197-100MG
25 mg
£ POA
HY-132197-25MG
50 mg
£ POA
HY-132197-50MG
10 mg
£ POA
HY-132197-10MG
10mM/1mL
£ POA
HY-132197-10MM
About this Product
SKU:
HY-132197
Application:
Antibody Microarray
CAS Number:
2738688-57-6
Extra Details:
CBP/p300-IN-12 is a potent and selective covalent histone acetyltransferases p300 (IC50 of 166 nM) and CBP inhibitor. CBP/p300-IN-12 decreases the levels of H3K27Ac of PC-3 cells (EC50 of 37 nM). CBP/p300-IN-12 forms a covalent adduct with C1450[1].
Molecular Weight:
667.61
Purity:
99.72
References:
[1]Anthony Mastracchio, et al. Discovery of a Potent and Selective Covalent p300/CBP Inhibitor. ACS Med Chem Lett. 2021 Apr 5;12(5):726-731.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Epigenetics
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