PD-1/PD-L1-IN-9 (hydrochloride)
Product Sizes
50 mg
£ POA
HY-132192A-50MG
5 mg
£ POA
HY-132192A-5MG
100 mg
£ POA
HY-132192A-100MG
10 mg
£ POA
HY-132192A-10MG
25 mg
£ POA
HY-132192A-25MG
10mM/1mL
£ POA
HY-132192A-10MM
About this Product
- SKU:
- HY-132192A
- Application:
- Antibody Microarray
- Extra Details:
- PD-1/PD-L1-IN-9 hydrochloride is a potent and orally active inhibitor of PD-1/PD-L1 interaction; with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 hydrochloride can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 hydrochloride also exhibits significant in vivo antitumor activity in a CT26 mouse model[1].
- Molecular Weight:
- 384.90
- Purity:
- 98.59
- References:
- [1]Wang T, et, al. Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2021 May 30.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
