PD-1/PD-L1-IN-9
Product Sizes
5 mg
£ POA
HY-132192-5MG
100 mg
£ POA
HY-132192-100MG
10 mg
£ POA
HY-132192-10MG
25 mg
£ POA
HY-132192-25MG
50 mg
£ POA
HY-132192-50MG
10mM/1mL
£ POA
HY-132192-10MM
About this Product
- SKU:
- HY-132192
- Application:
- Antibody Microarray
- CAS Number:
- 2628506-54-5
- Extra Details:
- PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction; with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model[1].
- Molecular Weight:
- 348.44
- Purity:
- 99.59
- References:
- [1]Wang T, et, al. Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2021 May 30.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
