MTEP (hydrochloride)
Product Sizes
5 mg
£ POA
HY-13206-5MG
10 mg
£ POA
HY-13206-10MG
50 mg
£ POA
HY-13206-50MG
10mM/1mL
£ POA
HY-13206-10MM
100 mg
£ POA
HY-13206-100MG
25 mg
£ POA
HY-13206-25MG
About this Product
- SKU:
- HY-13206
- CAS Number:
- 1186195-60-7
- Extra Details:
- MTEP hydrochloride is a potent; non-competitive and highly selective mGluR5 antagonist; with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. MTEP hydrochloride can be used for Parkinson's disease research[1][2][3][4].
- Molecular Weight:
- 236.72
- Purity:
- 99.79
- References:
- [1]Lea PM 4th, et al. Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. CNS Drug Rev. 2006 Summer;12(2):149-66.|[2]Ossowska K, et al. MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. Neuropharmacology. 2005 Sep;49(4):447-55.|[3]Pałucha A, et al. Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pharmacol Biochem Behav. 2005 Aug;81(4):901-6.|[4]Klodzinska A, et al. Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling. Neuropharmacology. 2004 Sep;47(3):342-50.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
