SP-96
Product Sizes
5 mg
£ POA
HY-131339-5MG
50 mg
£ POA
HY-131339-50MG
10 mg
£ POA
HY-131339-10MG
25 mg
£ POA
HY-131339-25MG
100 mg
£ POA
HY-131339-100MG
10mM/1mL
£ POA
HY-131339-10MM
About this Product
- SKU:
- HY-131339
- CAS Number:
- 2682114-54-9
- Extra Details:
- SP-96 is a highly potent; selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening; incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC)[1].
- Molecular Weight:
- 453.47
- Purity:
- 99.65
- References:
- [1]Naga Rajiv Lakkaniga,et al. Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression.Eur J Med Chem. 2020 Jul 12;203:112589.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Epigenetics
