Azido-PEG6-alcohol
Product Sizes
5 g
£ POA
HY-130537-5G
1 g
£ POA
HY-130537-1G
100 mg
£ POA
HY-130537-100MG
500 mg
£ POA
HY-130537-500MG
250 mg
£ POA
HY-130537-250MG
25 g
£ POA
HY-130537-25G
10 g
£ POA
HY-130537-10G
About this Product
- SKU:
- HY-130537
- Application:
- Antibody Microarray
- CAS Number:
- 86770-69-6
- Extra Details:
- Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG6-alcohol is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 307.34
- Purity:
- 98.0
- References:
- [1]Zorba A, et al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292.|[2]Loredana Vesci, et al. HDAC INHIBITORS-BASED ANTIBODY DRUG CONJUGATES (ADCs) AND USE IN THERAPY. WO2018178060A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
