Bromo-PEG2-C2-azide
Product Sizes
250 mg
£ POA
HY-130485-250MG
100 mg
£ POA
HY-130485-100MG
5 g
£ POA
HY-130485-5G
1 g
£ POA
HY-130485-1G
About this Product
- SKU:
- HY-130485
- Application:
- Antibody Microarray
- CAS Number:
- 530151-56-5
- Extra Details:
- Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG2-C2-azide is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 238.08
- Purity:
- 98.70
- References:
- [1]Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
