Azido-PEG9-acid
Product Sizes
500 mg
£ POA
HY-130475-500MG
250 mg
£ POA
HY-130475-250MG
100 mg
£ POA
HY-130475-100MG
1 g
£ POA
HY-130475-1G
5 g
£ POA
HY-130475-5G
About this Product
- SKU:
- HY-130475
- CAS Number:
- 1670249-37-2
- Extra Details:
- Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 511.56
- Purity:
- 97.74
- References:
- [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
