(Rac)-IBT6A
Product Sizes
50 mg
HY-13036-50MG
5 mg
HY-13036-5MG
10 mg
HY-13036-10MG
25 mg
HY-13036-25MG
100 mg
HY-13036-100MG
10mM/1mL
HY-13036-10MM
About this Product
- SKU:
- HY-13036
- CAS Number:
- 1412418-47-3
- Extra Details:
- (Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in synthesis of IBT6A Ibrutinib dimer and IBT6A adduct[1]. Ibrutinib is a selective; irreversible Btk inhibitor with an IC50 of 0.5 nM[2].
- Molecular Weight:
- 386.45
- Purity:
- 98.18
- References:
- [1]Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES.|[2]Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.|[3]Liu N, et al. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem. 2015 May 14;13(18):5147-57.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Protein Tyrosine Kinase/RTK
