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Proteins and Peptides

(R)-(-)-JQ1 Enantiomer

Product Sizes
100 mg
HY-13030A-100MG
25 mg
HY-13030A-25MG
50 mg
HY-13030A-50MG
5 mg
HY-13030A-5MG
10 mg
HY-13030A-10MG
10mM/1mL
HY-13030A-10MM
About this Product
SKU:
HY-13030A
Application:
Antibody Microarray
CAS Number:
1268524-71-5
Extra Details:
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes; whereas (R)-(-)-JQ1 Enantiomer has no effect.
Molecular Weight:
456.99
Purity:
99.79
References:
[1]Filippakopoulos, et al. Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73.|[2]Mahe M, et al. An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers. EMBO Mol Med. 2018 Apr;10(4). pii: e8163.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Epigenetics