Azido-PEG5-alcohol
Product Sizes
250 mg
£ POA
HY-130211-250MG
5 g
£ POA
HY-130211-5G
1 g
£ POA
HY-130211-1G
10 g
£ POA
HY-130211-10G
25 g
£ POA
HY-130211-25G
About this Product
- SKU:
- HY-130211
- Application:
- Antibody Microarray
- CAS Number:
- 86770-68-5
- Extra Details:
- Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 263.29
- Purity:
- 98.29
- References:
- [1]Zhang FL, et al. Molecular-target-based anticancer photosensitizer: synthesis and in vitro photodynamic activity of erlotinib-zinc(II) phthalocyanine conjugates. ChemMedChem. 2015 Feb;10(2):312-20.|[2] Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
