Azido-PEG8-NHS ester
Product Sizes
50 mg
£ POA
HY-130184-50MG
100 mg
£ POA
HY-130184-100MG
25 mg
£ POA
HY-130184-25MG
1 g
£ POA
HY-130184-1G
250 mg
£ POA
HY-130184-250MG
About this Product
- SKU:
- HY-130184
- Application:
- Antibody Microarray
- CAS Number:
- 1204834-00-3
- Extra Details:
- Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG8-NHS ester is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 564.58
- Purity:
- 99.72
- References:
- [1]Mahendra Persaud Deonarain, et al. Biological materials and uses thereof. WO2016046574A1.|[2]Rong Yuan, et al. Viruslike Element-Tagged Nanoparticle Inductively Coupled Plasma Mass Spectrometry Signal Multiplier: Membrane Biomarker Mediated Cell Counting. Analytical Chemistry (Washington, DC, United States) (2019), 91(8), 4948-4952.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
