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Proteins and Peptides

AP219

Product Sizes
1 mg (115.33 mM * 20 μL in Methylene chloride)
£ POA
HY-129303-1MG
5 mg (115.33 mM * 100 μL in Methylene chloride)
£ POA
HY-129303-5MG
About this Product
SKU:
HY-129303
Application:
Electron Microscopy
CAS Number:
779282-36-9
Extra Details:
AP39 (Item No. 17100) is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39; containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion.
Molecular Weight:
433.54
Purity:
99.67
References:
[1]Szczesny, et al. AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro. Nitric Oxide 41, 120-130 (2014).
Research Area:
Metabolic Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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