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CL2A

Product Sizes
10 mg
£ POA
HY-128945-10MG
100 mg
£ POA
HY-128945-100MG
50 mg
£ POA
HY-128945-50MG
5 mg
£ POA
HY-128945-5MG
About this Product
SKU:
HY-128945
CAS Number:
2616704-22-2
Extra Details:
CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity; giving rise to bystander effect; and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Molecular Weight:
1062.21
Purity:
98.20
References:
[1]Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related
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