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Proteins and Peptides

(4R;5S)-Nutlin carboxylic acid

Product Sizes
5 mg
£ POA
HY-128836-5MG
100 mg
£ POA
HY-128836-100MG
50 mg
£ POA
HY-128836-50MG
10 mg
£ POA
HY-128836-10MG
25 mg
£ POA
HY-128836-25MG
About this Product
SKU:
HY-128836
Additional Names:
MDM2 ligand 2; E3 ligase Ligand 15
Application:
Antibody Microarray
CAS Number:
2306390-08-7
Extra Details:
(4R;5S)-Nutlin carboxylic acid is a MDM2 ligand and also a nutlin-3 derivative. (4R;5S)-Nutlin carboxylic acid can be linked to target protein ligands via a linker to form a PROTAC that can be used for targeting PARP1[1].
Molecular Weight:
639.53
References:
[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
Research Area:
Others
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
PROTAC
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