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Proteins and Peptides

IFN alpha-IFNAR-IN-1 (hydrochloride)

Product Sizes
10 mg
£ POA
HY-12836A-10MG
5 mg
£ POA
HY-12836A-5MG
50 mg
£ POA
HY-12836A-50MG
100 mg
£ POA
HY-12836A-100MG
10mM/1mL
£ POA
HY-12836A-10MM
25 mg
£ POA
HY-12836A-25MG
About this Product
SKU:
HY-12836A
CAS Number:
2070014-98-9
Extra Details:
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic; low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived; Flt3- L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM)[1].
Molecular Weight:
315.86
Purity:
99.76
References:
[1]Geppert T, et al. Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):258-61.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation
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