Silperisone (hydrochloride)
Product Sizes
5 mg
HY-127004-5MG
1 mg
HY-127004-1MG
25 mg
HY-127004-25MG
10 mg
HY-127004-10MG
50 mg
HY-127004-50MG
About this Product
- SKU:
- HY-127004
- Additional Names:
- RGH-5002
- CAS Number:
- 140944-30-5
- Extra Details:
- Silperisone hydrochloride is an organosilicone compound similar to tolperisone that has centrally acting muscle relaxant properties. Silperisone (hydrochloride) is a sodium channel protein type 2 alpha channel blocker that blocks sodium and calcium channels in cells; reduces muscle cell excitability and contraction; reduces peripheral tone; and acts as a muscle relaxant and peripheral vascular dilator. Silperisone (hydrochloride) is used to study recurrent painful myoclonus due to spinal cord injury; abnormal hypertonia due to cerebrovascular disease; myotonia symptoms; pyramidal tonia syndrome; multiple sclerosis myospasm; and myelitis[1][2][3].
- Molecular Weight:
- 301.90
- References:
- [1]Farkas S, et al. Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs[J]. Journal of Pharmacological and Toxicological methods, 2005, 52(2): 264-273.|[2]Kocsis P, et al. Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels[J]. Journal of Pharmacology and Experimental Therapeutics, 2005, 315(3): 1237-1246.|[3]Farkas S, et al. Silperisone: a centrally acting muscle relaxant[J]. CNS Drug Reviews, 2006, 12(3‐4): 218-235.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel
