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Proteins and Peptides

(E/Z)-GSK-3β inhibitor 1

Product Sizes
10 mg
£ POA
HY-126144A-10MG
5 mg
£ POA
HY-126144A-5MG
50 mg
£ POA
HY-126144A-50MG
10mM/1mL
£ POA
HY-126144A-10MM
About this Product
SKU:
HY-126144A
Application:
Immunoprecipitation
CAS Number:
3367-88-2
Extra Details:
(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy; with an IC50 of 4.9 nM[1].
Molecular Weight:
222.24
Purity:
99.10
References:
[1]Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
Research Area:
Metabolic Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; protect from light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
PI3K/Akt/mTOR;Stem Cell/Wnt
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