(±)-8-Prenylnaringenin
Product Sizes
1 mg
£ POA
HY-126109-1MG
About this Product
- SKU:
- HY-126109
- Application:
- Immunoprecipitation
- CAS Number:
- 68682-02-0
- Extra Details:
- (±)-8-Prenylnaringenin; a natural prenylated flavonoid; is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM; respectively. (±)-8-Prenylnaringenin has anticancer effects; and can be used for osteoporosis research[1][2].
- Molecular Weight:
- 340.37
- Purity:
- 99.97
- References:
- [1]Kateřina Štulíková, et al. Therapeutic Perspectives of 8-Prenylnaringenin, a Potent Phytoestrogen from Hops. Molecules. 2018 Mar 15;23(3):660. |[2]Frederik Roelens, et al. Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. J Med Chem. 2006 Dec 14;49(25):7357-65. |[3]Song Park, et al. Naringenin and Phytoestrogen 8-Prenylnaringenin Protect against Islet Dysfunction and Inhibit Apoptotic Signaling in Insulin-Deficient Diabetic Mice. Molecules. 2022 Jun 30;27(13):4227.
- Research Area:
- Cancer; Endocrinology; Metabolic Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Vitamin D Related/Nuclear Receptor
