Murine Fibrinogen
Product Sizes
1 mg
£ POA
HY-125864B-1MG
About this Product
- SKU:
- HY-125864B
- CAS Number:
- 9001-32-5
- Extra Details:
- Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9); downregulates the expression of vascular endothelial cadherin (VE-cadherin); and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins; thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction[1].
- References:
- [1]Alving BM, et al. Rabbit fibrinogen: time course of constituent chain production in vivo. Arch Biochem Biophys. 1982 Aug;217(1):1-9.
- Research Area:
- Cardiovascular Disease;Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store at 4[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
