Glucose-6-phosphate dehydrogenase; Microorganism
Product Sizes
5 KU
£ POA
HY-125863-5KU
1 KU
£ POA
HY-125863-1KU
About this Product
- SKU:
- HY-125863
- Additional Names:
- G6PD
- Application:
- Immunoprecipitation
- CAS Number:
- 9001-40-5
- Extra Details:
- Glucose-6-phosphate dehydrogenase; Microorganism (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase; Microorganism is a primary source of NADPH in antioxidant pathways; nitric oxide synthase; NADPH oxidase; cytochrome p450 systems; and others. Glucose-6-phosphate dehydrogenase; Microorganism is applicable in research related to diabetes; endothelial dysfunction; cancer; and cardiomyopathy[1][2][3][4][5].
- Molecular Weight:
- N/A
- References:
- [1]Stanton RC. Glucose-6-phosphate dehydrogenase, NADPH, and cell survival. IUBMB Life. 2012 May;64(5):362-9.|[2]Zhang Z, et al. High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis. FASEB J. 2010 May;24(5):1497-505. |[3]Leopold JA, et al. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nat Med. 2007 Feb;13(2):189-97.|[4]Rajasekaran NS, et al. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell. 2007 Aug 10;130(3):427-39.|[5]Kuo W, et al. Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice. Int J Cancer. 2000 Mar 15;85(6):857-64.|[6]Sun L, et al. Kinetic properties of glucose 6-phosphate dehydrogenase and inhibition effects of several metal ions on enzymatic activity in vitro and cells. Sci Rep. 2024 Mar 9;14(1):5806.
- Research Area:
- Cancer; Metabolic Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Pathway:
- Metabolic Enzyme/Protease
