(S;R;S)-MI-1061
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HY-125858B-1EACH
About this Product
- SKU:
- HY-125858B
- CAS Number:
- 1410738-90-7
- Extra Details:
- (S;R;S)-MI-1061 is the isomer of MI-1061(HY-125858). (S;R;S)-MI-1061 can used to synthesize Antibody-Drug Conjugates (ADCs). MI-1061 is a potent; orally bioavailable; and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].
- Molecular Weight:
- 582.45
- References:
- [1]Nathan FISHKIN, et al. Linkers for use in antibody drug conjugates. WO2023037268A1.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
