CP-10
Product Sizes
5 mg
£ POA
HY-125835-5MG
1 mg
£ POA
HY-125835-1MG
10 mg
£ POA
HY-125835-10MG
50 mg
£ POA
HY-125835-50MG
10mM/1mL
£ POA
HY-125835-10MM
About this Product
- SKU:
- HY-125835
- CAS Number:
- 2366268-80-4
- Extra Details:
- CP-10 is a PROTAC connected by ligands for Cereblon and CDK; with highly selective; specific; and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma; and can still degrades mutated and overexpressed CDK6[1].
- Molecular Weight:
- 871.94
- Purity:
- 98.41
- References:
- [1]Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 2.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PROTAC
