IS20
Product Sizes
10 mg
£ POA
HY-125807-10MG
25 mg
£ POA
HY-125807-25MG
50 mg
£ POA
HY-125807-50MG
100 mg
£ POA
HY-125807-100MG
5 mg
£ POA
HY-125807-5MG
About this Product
- SKU:
- HY-125807
- CAS Number:
- 324561-95-7
- Extra Details:
- IS20 is a Prokineticin receptor 1 (PKR1) agonist. IS20 diminishes Doxorubicin (HY-15142A) mediated apoptosis and ROS production by activating Akt or MAPK pathways. IS20 protects the heart against Doxorubicin-induced cardiovascular toxicity and improves the survival rate and cardiac function in mouse models. IS20 does not alter the cytotoxicity and antitumor activity of acute DOX treatment in breast cancer cells and MDA-MB-231 xenograft mouse models. IS20 can be used for cancers research[1].
- Molecular Weight:
- 387.43
- Purity:
- 99.85
- Research Area:
- Cancer; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
