(rac)-AR-13503
Product Sizes
10 mg
£ POA
HY-125639-10MG
5 mg
£ POA
HY-125639-5MG
25 mg
£ POA
HY-125639-25MG
100 mg
£ POA
HY-125639-100MG
50 mg
£ POA
HY-125639-50MG
About this Product
- SKU:
- HY-125639
- Additional Names:
- (rac)-AR-13324 M1 metabolite
- CAS Number:
- 1254032-16-0
- Extra Details:
- (rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) is the isoform of AR-13503 (HY-12798C). AR-13503 a ROCK/PKC inhibitor; inhibiting angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. AR-13503 also inhibits the formation of aberrant neovascularization (NV) in oxygen-induced retinopathy (OIR) model in mice[1][2].
- Molecular Weight:
- 321.37
- Purity:
- 99.08
- References:
- [1]Ding J, et al. ROCK/PKC inhibitor AR-13503 inhibits angiogenesis and protects the barrier function of retinal pigment epithelium[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 205-205. |[2]Carbajal K, et al. AR-13503 Enhances the efficacy of aflibercept in a mouse model of proliferative diabetic retinopathy[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 200-200.
- Research Area:
- Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Cytoskeleton;Epigenetics;Stem Cell/Wnt;TGF-beta/Smad
