(7R)-SBP-0636457
Product Sizes
25 mg
£ POA
HY-125378A-25MG
50 mg
£ POA
HY-125378A-50MG
10 mg
£ POA
HY-125378A-10MG
5 mg
£ POA
HY-125378A-5MG
About this Product
- SKU:
- HY-125378A
- Additional Names:
- (7R)-SBI-0636457; (7R)-SB1-0636457
- Application:
- Antibody Microarray
- CAS Number:
- 1422180-61-7
- Extra Details:
- (7R)-SBP-0636457 is the isomer of SBP-0636457 (HY-125378); and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic; and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins; with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2].
- Molecular Weight:
- 456.58
- Purity:
- 98.36
- References:
- [1]Finlay D, et, al. Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. Mol Cancer Ther. 2014 Jan; 13(1): 5-15.|[2]Finlay D, et, al. Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. F1000Res. 2017 Apr 27; 6:587.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis
